Sex hormone-binding globulin and type 2 diabetes mellitus

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منابع مشابه

The Evaluation of Serum Level of Testosterone and Sex Hormone- Binding Globulin in Men with Type 2 Diabetes

OBJECTIVE: To evaluate the relationship between serum level of testosterone and sex hormone-binding globulin in men with type 2 diabetes. MATERIALS AND METHODS: In this case-control study, forty men aged 40-70 with type 2 diabetes mellitus were randomly selected and compared with 40 non-diabetic men. The two groups were matched for their age and BMI. After complete observation and examination...

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Sex hormone-binding globulin and risk of type 2 diabetes.

BACKGROUND Circulating sex hormone-binding globulin levels are inversely associated with insulin resistance, but whether these levels can predict the risk of developing type 2 diabetes is uncertain. METHODS We performed a nested case-control study of postmenopausal women in the Women's Health Study who were not using hormone therapy (359 with newly diagnosed type 2 diabetes and 359 controls)....

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Sex hormone-binding globulin as an independent predictor of incident type 2 diabetes mellitus in men.

BACKGROUND Low levels of sex hormone-binding globulin (SHBG) and total testosterone (T) in men have been associated with increased risk of type 2 diabetes mellitus (T2DM). As total T and SHBG levels are highly correlated, we determined whether SHBG influences the risk of T2DM through T or whether SHBG is an independent predictor of T2DM. METHODS Longitudinal analyses were conducted on men par...

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Study of Sex Hormone-Binding Globulin in Type 2 Diabetes Mellitus

Background: Sex hormone-binding globulin (SHBG) regulates the levels of free sex hormones by sequestering circulating sex hormones and participates in some of the biological actions of sex hormones by mediating cellular uptake. Low circulating levels of sex hormone–binding globulin are a strong predictor of the risk of type 2 diabetes in women and men. However, it has been difficult to determin...

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the evaluation of serum level of testosterone and sex hormone- binding globulin in men with type 2 diabetes

objective: to evaluate the relationship between serum level of testosterone and sex hormone-binding globulin in men with type 2 diabetes. materials and methods: in this case-control study, forty men aged 40-70 with type 2 diabetes mellitus were randomly selected and compared with 40 non-diabetic men. the two groups were matched for their age and bmi. after complete observation and examination, ...

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ژورنال

عنوان ژورنال: Trends in Endocrinology & Metabolism

سال: 2012

ISSN: 1043-2760

DOI: 10.1016/j.tem.2011.09.005